Dogs:
For pregnancy avoidance after mismating:
a) 0.1 - 1 mg PO for 5 days if animal is presented 24-48 hours after coitus. If animal is presented later than 5 days post-coitus: 1 - 2 mg PO for 5 days after ECP therapy (0.044 mg/kg (ECP) IM once during 3-5 days of standing heat or within 72 hours of mis-mating)
For treatment of perianal gland adenomas and prostatic hyperplasias:
a) 0.1 - 1 mg PO q24-48h
b) 1 mg PO q72h; or 1.1 mg/kg once. Do not administer more than 25 mg.
For treatment of estrogen-responsive incontinence:
a) Initially 0.1 - 1 mg PO daily for 3-5 days, followed by maintenance therapy of approximately 1 mg PO per week. Some animals may require much higher initial dosages
to obtain a response. Maximum initial doses of 0.1 - 0.3 mg/kg once daily for 7 days,
then reduce to once weekly. All maintenance doses should be gradually reduced to the
lowest effective dose.
b) 0.1 - 1 mg PO per day for 3-5 days, then 1 mg once weekly
c) 0.1 - 1 mg PO for 3-5 days followed by 1 mg every week or less often. Some animals
may require more than 1 mg weekly to maintain. (
